Xiaoyi Wu

Courses

Finite Element Methods

AME 561

Mech Behav Eng Materials

AME 324A

Mech Deformable Solids

AME 564A

Numerical Methods

AME 302

Mech Behav Eng Materials

AME 324A

Micro Biomechanics

BME 583

Research

AME 900

Mech Deformable Solids

AME 564A (Fall 2023)

Scholarly Contributions

Journals/Publications

• Chen, H., Ma, Y., Wang, X., Wu, X., & Zha, Z. (2017). Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer. RSC ADVANCES, 7(1), 248-255.
• Wang, X., Ma, Y., Chen, H., Wu, X., Qian, H., Yang, X., & Zha, Z. (2017). Novel doxorubicin loaded PEGylated cuprous telluride nanocrystals for combined photothermal-chemo cancer treatment. COLLOIDS AND SURFACES B-BIOINTERFACES, 152, 449-458.
• Cohn, C., Leung, S. L., Crosby, J., Lafuente, B., Zha, Z., Teng, W., Downs, R., & Wu, X. (2016). Lipid-mediated protein functionalization of electro spun polycaprolactone fibers. EXPRESS POLYMER LETTERS, 10(5), 430-437.
• Teng, W., Zhang, X., Merkle, V., & Wu, X. (2016). Deformation-induced mechanical anisotropy of gelatin films. Extreme Mechanics Letters, 7, 18-26. doi:10.1016/j.eml.2016.02.010
• Cohn, C., Leung, S. L., Zha, Z., Crosby, J., Teng, W., & Wu, X. (2015). Comparative study of antibody immobilization mediated by lipid and polymer fibers. COLLOIDS AND SURFACES B-BIOINTERFACES, 134, 1-7.
• Merkle, V. M., Martin, D., Hutchinson, M., Tran, P. L., Behrens, A., Hossainy, S., Sheriff, J., Bluestein, D., Wu, X., & Slepian, M. J. (2015). Hemocompatibility of Poly(vinyl alcohol)-Gelatin Core-Shell Electro spun Nanofibers: A Scaffold for Modulating Platelet Deposition and Activation. ACS APPLIED MATERIALS & INTERFACES, 7(15), 8302-8312.
• Merkle, V. M., Martin, D., Hutchinson, M., Tran, P. L., Behrens, A., Hossainy, S., Sheriff, J., Bluestein, D., Wu, X., & Slepian, M. J. (2015). Hemocompatibility of Poly(vinyl alcohol)-Gelatin Core-Shell Electro spun Nanofibers: A Scaffold for Modulating Platelet Deposition and Activation. ACS applied materials & interfaces, 7(15), 8302-12.
• Merkle, V. M., Tran, P. L., Hutchinson, M., Ammann, K. R., DeCook, K., Wu, X., & Slepian, M. J. (2015). Core-shell PVA/gelatin electro spun nanofibers promote human umbilical vein endothelial cell and smooth muscle cell proliferation and migration. ACTA BIOMATERIALIA, 27, 77-87.
• Leung, S. L., Zha, Z., Cohn, C., Dai, Z., & Wu, X. (2014). Anti-EGFR Antibody Conjugated Organic-inorganic Hybrid Lipid Nanovesicles Selectively Target Tumor Cells. Colloids and Surfaces B: Biointerfaces, 121, 141-149.
• Merkle, V. M., Zeng, L., Slepian, M. J., & Wu, X. (2014). Core-shell Nanofibers: Integrating the Bioactivity of Gelatin and the Mechanical Property of Polyvinyl Alcohol. Biopolymers, 101(4), 336-346.
• Zeng, L., Jiang, L., Teng, W., Cappello, J., Zohar, Y., & Wu, X. (2014). Engineering Aqueous Fiber Assembly into Silk-elastin-like Protein Polymers. Macromolecular Rapid Communications, 35(14), 1273-1279.
• Zeng, L., Teng, W., Jiang, L., Cappello, J., & Wu, X. (2014). Ordering Recombinant Silk-elastic-like Nanofibers on the Microscale. Applied Physics Letters, 104(3), 033702.
• Merkle, V. M., Ammann, K. R., DeCook, K. J., Tran, P. L., Slepian, M. J., & Xiaoyi, W. u. (2013). In vitro biocompatibility of coaxial electro spun scaffolds for cardiovascular tissue engineering. ASME 2013 Summer Bioengineering Conference, SBC 2013, 1 A.
• Merkle, V. M., Hutchinson, M., Tran, P. L., Sheriff, J., Bluestein, D., Xiaoyi, W. u., & Slepian, M. J. (2013). Platelet activity of coaxial electro spun scaffolds for applications in cardiovascular tissue engineering. ASME 2013 Summer Bioengineering Conference, SBC 2013, 1 A.
• Merkle, V., Zeng, L., Teng, W., Slepian, M., & Wu, X. (2013). Gelatin shells strengthen polyvinyl alcohol core-shell nanofibers. POLYMER, 54(21), 6003-6007.
• Merkle, V., Zeng, L., Teng, W., Slepian, M., & Wu, X. (2013). Gelatin shells strengthen polyvinyl alcohol core-shell nanofibers. Polymer (United Kingdom), 54(21), 6003-6007.
• Cao, Z., Yue, X., Jin, Y., Wu, X., & Dai, Z. (2012). Modulation of release of paclitaxel from composite cerasomes. COLLOIDS AND SURFACES B-BIOINTERFACES, 98, 97-104.
• Cao, Z., Yue, X., Jin, Y., Xiaoyi, W. u., & Dai, Z. (2012). Modulation of release of paclitaxel from composite cerasomes. Colloids and Surfaces B: Biointerfaces, 98, 97-104.
• Guo, C., Zeng, L., Liu, S., Chen, Q., Dai, Z., & Wu, X. (2012). In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. Journal of Nanoscience and Nanotechnology, 12(1), 245-251.
• Jin, Y., Yue, X., Zhang, Q., Wu, X., Cao, Z., & Dai, Z. (2012). Cerasomal doxorubicin with long-term storage stability and controllable sustained release. ACTA BIOMATERIALIA, 8(9), 3372-3380.
• Jin, Y., Yue, X., Zhang, Q., Xiaoyi, W. u., Cao, Z., & Dai, Z. (2012). Cerasomal doxorubicin with long-term storage stability and controllable sustained release. Acta Biomaterialia, 8(9), 3372-3380.
• Leung, S. L., Zha, Z., Teng, W., Cohn, C., Dai, Z., & Wu, X. (2012). Organic-inorganic nanovesicles for doxorubicin storage and release. Soft Matter, 8(21), 5756-5764.
• Merkle, V., & Xiaoyi, W. u. (2012). Coaxial electrospinning of gelatin/polyvinyl alcohol composite nanofibers and evaluation of their material properties. 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012, 380-381.
• Zha, Z., Jiang, L., Dai, Z., & Wu, X. -. (2012). A biomimetic mechanism for antibody immobilization on lipid nanofibers for cell capture. Applied physics letters, 101(19).
• Zha, Z., Leung, S. L., Dai, Z., & Wu, X. (2012). Centering of organic-inorganic hybrid liposomal cerasomes in electro spun gelatin nanofibers. Applied Physics Letters, 100(3).
• Zha, Z., Teng, W., Markle, V., Dai, Z., & Wu, X. (2012). Fabrication of gelatin nanofibrous scaffolds using ethanol/phosphate buffer saline as a benign solvent. BIOPOLYMERS, 97(12), 1026-1036.
• Zha, Z., Teng, W., Markle, V., Dai, Z., & Wu, X. -. (2012). Fabrication of gelatin nanofibrous scaffolds using ethanol/phosphate buffer saline as a benign solvent. Biopolymers, 97(12).
• Qiu, W., Cappello, J., & Wu, X. (2011). Autoclaving as a chemical-free process to stabilize recombinant silk-elastin like protein polymer nanofibers. Applied Physics Letters, 98(26).
• Teng, W., Cappello, J., & Wu, X. (2011). Physical crosslinking modulates sustained drug release from recombinant silk-elastin like protein polymer for ophthalmic applications. JOURNAL OF CONTROLLED RELEASE, 156(2), 186-194.
• Teng, W., Cappello, J., & Wu, X. -. (2011). Physical crosslinking modulates sustained drug release from recombinant silk-elastin like protein polymer for ophthalmic applications. Journal of controlled release : official journal of the Controlled Release Society, 156(2).
• Teng, W., Huang, Y., Cappello, J., & Wu, X. (2011). Optically Transparent Recombinant Silk-Elastin like Protein Polymer Films. JOURNAL OF PHYSICAL CHEMISTRY B, 115(7), 1608-1615.
• Teng, W., Huang, Y., Cappello, J., & Wu, X. -. (2011). Optically transparent recombinant silk-elastin like protein polymer films. The journal of physical chemistry. B, 115(7).
• Zeng, L., An, L., & Wu, X. -. (2011). Modeling drug-carrier interaction in the drug release from nanocarriers. Journal of drug delivery, 2011.
• Zha, Z., Cohn, C., Dai, Z., Qiu, W., Zhang, J., & Wu, X. -. (2011). Nanofibrous lipid membranes capable of functionally immobilizing antibodies and capturing specific cells. Advanced materials (Deerfield Beach, Fla.), 23(30).
• Qiu, W., Huang, Y., Cappello, J., & Xiaoyi, W. u. (2010). Electro spun recombinant protein polymer nanofibers as a biomaterial. Proceedings of the ASME 1st Global Congress on Nano Engineering for Medicine and Biology 2010, NEMB2010, 207-208.
• Qiu, W., Huang, Y., Teng, W., Cohn, C. M., Cappello, J., & Wu, X. (2010). Complete Recombinant Silk-Elastin like Protein-Based Tissue Scaffold. BIOMACROMOLECULES, 11(12), 3219-3227.
• Qiu, W., Huang, Y., Teng, W., Cohn, C. M., Cappello, J., & Wu, X. -. (2010). Complete recombinant silk-elastin like protein-based tissue scaffold. Biomacromolecules, 11(12).
• Teng, W., Huang, Y., Cappello, J., & Xiaoyi, W. u. (2010). Mechanical and in-vitro cell compatibility properties of silk-elastin like protein-based biomaterial. Proceedings of the ASME 1st Global Congress on Nano Engineering for Medicine and Biology 2010, NEMB2010, 209-210.
• Zeng, L., & Wu, X. (2010). Modeling the sustained release of lipophilic drugs from liposomes. Applied Physics Letters, 97(7).
• Guo, C., Liu, S., Jiang, C., Li, W., Dai, Z., Fritz, H., & Wu, X. (2009). A Promising Drug Controlled-Release System Based on Diacetylene/Phospholipid Polymerized Vesicles. LANGMUIR, 25(22), 13114-13119.
  Guo, C., Liu, S., Jiang, C., Li, W., Dai, Z., Fritz, H., & Wu, X. (2009). A promising drug controlled-release system based on diacetylene/ phospholipid polymerized vesicles. Langmuir, 25(22), 13114-13119.
• Qiu, W., Cappello, J., & Xiaoyi, W. u. (2009). Fabrication of genetically engineered silk-elastin-like protein polymer fibers. Proceedings of the ASME Summer Bioengineering Conference, SBC2008, 179-180.
• Qiu, W., Stokes, A., Cappello, J., & Xiaoyi, W. u. (2009). Electrospinning of recombinant protein polymer nanofibers. Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 1183-1184.
• Qiu, W., Teng, W., Cappello, J., & Wu, X. (2009). Wet-Spinning of Recombinant Silk-Elastin-Like Protein Polymer Fibers with High Tensile Strength and High Deformability. BIOMACROMOLECULES, 10(3), 602-608.
• Qiu, W., Teng, W., Cappello, J., & Wu, X. -. (2009). Wet-spinning of recombinant silk-elastin-like protein polymer fibers with high tensile strength and high deformability. Biomacromolecules, 10(3).
• Teng, W., Cappello, J., & Wu, X. (2009). Recombinant Silk-Elastin like Protein Polymer Displays Elasticity Comparable to Elastin. BIOMACROMOLECULES, 10(11), 3028-3036.
• Teng, W., Cappello, J., & Wu, X. -. (2009). Recombinant silk-elastin like protein polymer displays elasticity comparable to elastin. Biomacromolecules, 10(11).
• Teng, W., Cappello, J., & Xiaoyi, W. u. (2009). Secondary structures and mechanical properties of biomimetic protein polymers. Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 797-798.
• Teng, W., Cappello, J., & Xiaoyi, W. u. (2009). Viscoelastic properties of genetically engineered silk-elastin-like protein polymers. Proceedings of the ASME Summer Bioengineering Conference, SBC2008, 231-232.
  Keyes, J., Junkin, M., Cappello, J., Xiaoyi, W. u., & Wong, P. K. (2008). Evaporation-induced assembly of biomimetic polypeptides. Applied Physics Letters, 93(2).
• Wu, X., Sallach, R. E., Caves, J. M., Conticello, V. P., & Chaikof, E. L. (2008). Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. BIOMACROMOLECULES, 9(7), 1787-1794.
• Wu, X., Sallach, R. E., Caves, J. M., Conticello, V. P., & Chaikof, E. L. (2008). Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. Biomacromolecules, 9(7), 1787-1794.
• Wu, X., Levenston, M. E., & Chaikof, E. L. (2006). A constitutive model for protein-based materials. BIOMATERIALS, 27(30), 5315-5325.
• Wu, X., Levenston, M. E., & Chaikof, E. L. (2006). A constitutive model for protein-based materials. Biomaterials, 27(30), 5315-5325.
• Dong, C., Xiaoyi, W. u., Caves, J., Rele, S. S., Thomas, B. S., & Chaikof, E. L. (2005). Photo mediated crosslinking of C6-cinnamate derivatized type I collagen. Biomaterials, 26(18), 4041-4049.
• Nagapudi, K., Brinkman, W. T., Leisen, J., Thomas, B. S., Wright, E. R., Haller, C., Xiaoyi, W. u., Apkarian, R. P., Conticello, V. P., & Chaikof, E. L. (2005). Protein-based thermoplastic elastomers. Macromolecules, 38(2), 345-354.
• Sun, X., Haller, C. A., XiaoYi, W. u., Conticello, V. P., & Chaikof, E. L. (2005). One-pot glyco-affinity precipitation purification for enhanced proteomics: The flexible alignment of solution-phase capture/release and solid-phase separation. Journal of Proteome Research, 4(6), 2355-2359.
• Wu, X., Sallach, R., Haller, C. A., Caves, J. A., Nagapudi, K., Conticello, V. P., Levenston, M. E., & Chaikof, E. L. (2005). Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks. Biomacromolecules, 6(6), 3037-3044.
• Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The coupled effects of plastic strain gradient and thermal softening on the dynamic growth of voids. International Journal of Solids and Structures, 40(24), 6633-6651.
• Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The dynamic growth of a single void in a visco plastic material under transient hydrostatic loading. Journal of the Mechanics and Physics of Solids, 51(1), 1-26.
• Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The effects of thermal softening and heat conduction on the dynamic growth of voids. International Journal of Solids and Structures, 40(17), 4461-4478.

Proceedings Publications

• Nicolini, A. M., Cohn, C. M., Gamboa, J. R., Slepian, M. J., Wu, X., & Yoon, J. (2014, Apr). Fabrication of a pro-adhesive surface using electro spun PCL nanofibers interspersed with peptide conjugated polystyrene particles. In IEEE-NEMS 2014.

Presentations

• Cohn, C., Frazer, L., Pearse, M., Leung, S., & Wu, X. (2014, February 28). Engineering Cholesterol-based Nanostructures as Diagnostic Platforms. BME Founder's Day. University of Arizona, Tucson, AZ.
• Cohn, C., Frazer, L., Pearse, M., Leung, S., & Wu, X. (2014, October 22-25). Engineering Minimally Invasive Diagnostic Platforms with Cholesterol-based Nanostructures. Biomedical Engineering Society Annual Meeting. San Antonio, TX.
• Nicolini, A. M., Cohn, C. M., Slepian, M. J., Wu, X., & Yoon, J. (2014, Mar). Fabrication of a pro-adhesive surface using electro spun PCL nanofibers interspersed with peptide conjugated polystyrene particles. Annual Meeting of IBE. Lexington, KY: IBE.

Others

• Wu, X. (2016, May). Bioinspired Materials for Applications in Regenerative Medicine.
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