Xiaoyi Wu

Associate Professor of Aerospace and Mechanical Engineering
Associate Professor, BIO5 Institute
Member of the Graduate Faculty
Xiaoyi Wu

AME N716

520.626.5854
xwu@arizona.edu

Scholarly Contributions

Journals/Publications

  • Chen, H., Ma, Y., Wang, X., Wu, X., & Zha, Z. (2017). Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer. RSC ADVANCES, 7(1), 248-255.
  • Wang, X., Ma, Y., Chen, H., Wu, X., Qian, H., Yang, X., & Zha, Z. (2017). Novel doxorubicin loaded PEGylated cuprous telluride nanocrystals for combined photothermal-chemo cancer treatment. COLLOIDS AND SURFACES B-BIOINTERFACES, 152, 449-458.
  • Cohn, C., Leung, S. L., Crosby, J., Lafuente, B., Zha, Z., Teng, W., Downs, R., & Wu, X. (2016). Lipid-mediated protein functionalization of electro spun polycaprolactone fibers. EXPRESS POLYMER LETTERS, 10(5), 430-437.
  • Teng, W., Zhang, X., Merkle, V., & Wu, X. (2016). Deformation-induced mechanical anisotropy of gelatin films. Extreme Mechanics Letters, 7, 18-26. doi:10.1016/j.eml.2016.02.010
  • Cohn, C., Leung, S. L., Zha, Z., Crosby, J., Teng, W., & Wu, X. (2015). Comparative study of antibody immobilization mediated by lipid and polymer fibers. COLLOIDS AND SURFACES B-BIOINTERFACES, 134, 1-7.
  • Merkle, V. M., Martin, D., Hutchinson, M., Tran, P. L., Behrens, A., Hossainy, S., Sheriff, J., Bluestein, D., Wu, X., & Slepian, M. J. (2015). Hemocompatibility of Poly(vinyl alcohol)-Gelatin Core-Shell Electro spun Nanofibers: A Scaffold for Modulating Platelet Deposition and Activation. ACS APPLIED MATERIALS & INTERFACES, 7(15), 8302-8312.
  • Merkle, V. M., Martin, D., Hutchinson, M., Tran, P. L., Behrens, A., Hossainy, S., Sheriff, J., Bluestein, D., Wu, X., & Slepian, M. J. (2015). Hemocompatibility of Poly(vinyl alcohol)-Gelatin Core-Shell Electro spun Nanofibers: A Scaffold for Modulating Platelet Deposition and Activation. ACS applied materials & interfaces, 7(15), 8302-12.
  • Merkle, V. M., Tran, P. L., Hutchinson, M., Ammann, K. R., DeCook, K., Wu, X., & Slepian, M. J. (2015). Core-shell PVA/gelatin electro spun nanofibers promote human umbilical vein endothelial cell and smooth muscle cell proliferation and migration. ACTA BIOMATERIALIA, 27, 77-87.
  • Leung, S. L., Zha, Z., Cohn, C., Dai, Z., & Wu, X. (2014). Anti-EGFR Antibody Conjugated Organic-inorganic Hybrid Lipid Nanovesicles Selectively Target Tumor Cells. Colloids and Surfaces B: Biointerfaces, 121, 141-149.
  • Merkle, V. M., Zeng, L., Slepian, M. J., & Wu, X. (2014). Core-shell Nanofibers: Integrating the Bioactivity of Gelatin and the Mechanical Property of Polyvinyl Alcohol. Biopolymers, 101(4), 336-346.
  • Zeng, L., Jiang, L., Teng, W., Cappello, J., Zohar, Y., & Wu, X. (2014). Engineering Aqueous Fiber Assembly into Silk-elastin-like Protein Polymers. Macromolecular Rapid Communications, 35(14), 1273-1279.
  • Zeng, L., Teng, W., Jiang, L., Cappello, J., & Wu, X. (2014). Ordering Recombinant Silk-elastic-like Nanofibers on the Microscale. Applied Physics Letters, 104(3), 033702.
  • Merkle, V. M., Ammann, K. R., DeCook, K. J., Tran, P. L., Slepian, M. J., & Xiaoyi, W. u. (2013). In vitro biocompatibility of coaxial electro spun scaffolds for cardiovascular tissue engineering. ASME 2013 Summer Bioengineering Conference, SBC 2013, 1 A.
  • Merkle, V. M., Hutchinson, M., Tran, P. L., Sheriff, J., Bluestein, D., Xiaoyi, W. u., & Slepian, M. J. (2013). Platelet activity of coaxial electro spun scaffolds for applications in cardiovascular tissue engineering. ASME 2013 Summer Bioengineering Conference, SBC 2013, 1 A.
  • Merkle, V., Zeng, L., Teng, W., Slepian, M., & Wu, X. (2013). Gelatin shells strengthen polyvinyl alcohol core-shell nanofibers. POLYMER, 54(21), 6003-6007.
  • Merkle, V., Zeng, L., Teng, W., Slepian, M., & Wu, X. (2013). Gelatin shells strengthen polyvinyl alcohol core-shell nanofibers. Polymer (United Kingdom), 54(21), 6003-6007.
  • Cao, Z., Yue, X., Jin, Y., Wu, X., & Dai, Z. (2012). Modulation of release of paclitaxel from composite cerasomes. COLLOIDS AND SURFACES B-BIOINTERFACES, 98, 97-104.
  • Cao, Z., Yue, X., Jin, Y., Xiaoyi, W. u., & Dai, Z. (2012). Modulation of release of paclitaxel from composite cerasomes. Colloids and Surfaces B: Biointerfaces, 98, 97-104.
  • Guo, C., Zeng, L., Liu, S., Chen, Q., Dai, Z., & Wu, X. (2012). In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles. Journal of Nanoscience and Nanotechnology, 12(1), 245-251.
  • Jin, Y., Yue, X., Zhang, Q., Wu, X., Cao, Z., & Dai, Z. (2012). Cerasomal doxorubicin with long-term storage stability and controllable sustained release. ACTA BIOMATERIALIA, 8(9), 3372-3380.
  • Jin, Y., Yue, X., Zhang, Q., Xiaoyi, W. u., Cao, Z., & Dai, Z. (2012). Cerasomal doxorubicin with long-term storage stability and controllable sustained release. Acta Biomaterialia, 8(9), 3372-3380.
  • Leung, S. L., Zha, Z., Teng, W., Cohn, C., Dai, Z., & Wu, X. (2012). Organic-inorganic nanovesicles for doxorubicin storage and release. Soft Matter, 8(21), 5756-5764.
  • Merkle, V., & Xiaoyi, W. u. (2012). Coaxial electrospinning of gelatin/polyvinyl alcohol composite nanofibers and evaluation of their material properties. 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012, 380-381.
  • Zha, Z., Jiang, L., Dai, Z., & Wu, X. -. (2012). A biomimetic mechanism for antibody immobilization on lipid nanofibers for cell capture. Applied physics letters, 101(19).
  • Zha, Z., Leung, S. L., Dai, Z., & Wu, X. (2012). Centering of organic-inorganic hybrid liposomal cerasomes in electro spun gelatin nanofibers. Applied Physics Letters, 100(3).
  • Zha, Z., Teng, W., Markle, V., Dai, Z., & Wu, X. (2012). Fabrication of gelatin nanofibrous scaffolds using ethanol/phosphate buffer saline as a benign solvent. BIOPOLYMERS, 97(12), 1026-1036.
  • Zha, Z., Teng, W., Markle, V., Dai, Z., & Wu, X. -. (2012). Fabrication of gelatin nanofibrous scaffolds using ethanol/phosphate buffer saline as a benign solvent. Biopolymers, 97(12).
  • Qiu, W., Cappello, J., & Wu, X. (2011). Autoclaving as a chemical-free process to stabilize recombinant silk-elastin like protein polymer nanofibers. Applied Physics Letters, 98(26).
  • Teng, W., Cappello, J., & Wu, X. (2011). Physical crosslinking modulates sustained drug release from recombinant silk-elastin like protein polymer for ophthalmic applications. JOURNAL OF CONTROLLED RELEASE, 156(2), 186-194.
  • Teng, W., Cappello, J., & Wu, X. -. (2011). Physical crosslinking modulates sustained drug release from recombinant silk-elastin like protein polymer for ophthalmic applications. Journal of controlled release : official journal of the Controlled Release Society, 156(2).
  • Teng, W., Huang, Y., Cappello, J., & Wu, X. (2011). Optically Transparent Recombinant Silk-Elastin like Protein Polymer Films. JOURNAL OF PHYSICAL CHEMISTRY B, 115(7), 1608-1615.
  • Teng, W., Huang, Y., Cappello, J., & Wu, X. -. (2011). Optically transparent recombinant silk-elastin like protein polymer films. The journal of physical chemistry. B, 115(7).
  • Zeng, L., An, L., & Wu, X. -. (2011). Modeling drug-carrier interaction in the drug release from nanocarriers. Journal of drug delivery, 2011.
  • Zha, Z., Cohn, C., Dai, Z., Qiu, W., Zhang, J., & Wu, X. -. (2011). Nanofibrous lipid membranes capable of functionally immobilizing antibodies and capturing specific cells. Advanced materials (Deerfield Beach, Fla.), 23(30).
  • Qiu, W., Huang, Y., Cappello, J., & Xiaoyi, W. u. (2010). Electro spun recombinant protein polymer nanofibers as a biomaterial. Proceedings of the ASME 1st Global Congress on Nano Engineering for Medicine and Biology 2010, NEMB2010, 207-208.
  • Qiu, W., Huang, Y., Teng, W., Cohn, C. M., Cappello, J., & Wu, X. (2010). Complete Recombinant Silk-Elastin like Protein-Based Tissue Scaffold. BIOMACROMOLECULES, 11(12), 3219-3227.
  • Qiu, W., Huang, Y., Teng, W., Cohn, C. M., Cappello, J., & Wu, X. -. (2010). Complete recombinant silk-elastin like protein-based tissue scaffold. Biomacromolecules, 11(12).
  • Teng, W., Huang, Y., Cappello, J., & Xiaoyi, W. u. (2010). Mechanical and in-vitro cell compatibility properties of silk-elastin like protein-based biomaterial. Proceedings of the ASME 1st Global Congress on Nano Engineering for Medicine and Biology 2010, NEMB2010, 209-210.
  • Zeng, L., & Wu, X. (2010). Modeling the sustained release of lipophilic drugs from liposomes. Applied Physics Letters, 97(7).
  • Guo, C., Liu, S., Jiang, C., Li, W., Dai, Z., Fritz, H., & Wu, X. (2009). A Promising Drug Controlled-Release System Based on Diacetylene/Phospholipid Polymerized Vesicles. LANGMUIR, 25(22), 13114-13119.
    Guo, C., Liu, S., Jiang, C., Li, W., Dai, Z., Fritz, H., & Wu, X. (2009). A promising drug controlled-release system based on diacetylene/ phospholipid polymerized vesicles. Langmuir, 25(22), 13114-13119.
  • Qiu, W., Cappello, J., & Xiaoyi, W. u. (2009). Fabrication of genetically engineered silk-elastin-like protein polymer fibers. Proceedings of the ASME Summer Bioengineering Conference, SBC2008, 179-180.
  • Qiu, W., Stokes, A., Cappello, J., & Xiaoyi, W. u. (2009). Electrospinning of recombinant protein polymer nanofibers. Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 1183-1184.
  • Qiu, W., Teng, W., Cappello, J., & Wu, X. (2009). Wet-Spinning of Recombinant Silk-Elastin-Like Protein Polymer Fibers with High Tensile Strength and High Deformability. BIOMACROMOLECULES, 10(3), 602-608.
  • Qiu, W., Teng, W., Cappello, J., & Wu, X. -. (2009). Wet-spinning of recombinant silk-elastin-like protein polymer fibers with high tensile strength and high deformability. Biomacromolecules, 10(3).
  • Teng, W., Cappello, J., & Wu, X. (2009). Recombinant Silk-Elastin like Protein Polymer Displays Elasticity Comparable to Elastin. BIOMACROMOLECULES, 10(11), 3028-3036.
  • Teng, W., Cappello, J., & Wu, X. -. (2009). Recombinant silk-elastin like protein polymer displays elasticity comparable to elastin. Biomacromolecules, 10(11).
  • Teng, W., Cappello, J., & Xiaoyi, W. u. (2009). Secondary structures and mechanical properties of biomimetic protein polymers. Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009, 797-798.
  • Teng, W., Cappello, J., & Xiaoyi, W. u. (2009). Viscoelastic properties of genetically engineered silk-elastin-like protein polymers. Proceedings of the ASME Summer Bioengineering Conference, SBC2008, 231-232.
    Keyes, J., Junkin, M., Cappello, J., Xiaoyi, W. u., & Wong, P. K. (2008). Evaporation-induced assembly of biomimetic polypeptides. Applied Physics Letters, 93(2).
  • Wu, X., Sallach, R. E., Caves, J. M., Conticello, V. P., & Chaikof, E. L. (2008). Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. BIOMACROMOLECULES, 9(7), 1787-1794.
  • Wu, X., Sallach, R. E., Caves, J. M., Conticello, V. P., & Chaikof, E. L. (2008). Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer. Biomacromolecules, 9(7), 1787-1794.
  • Wu, X., Levenston, M. E., & Chaikof, E. L. (2006). A constitutive model for protein-based materials. BIOMATERIALS, 27(30), 5315-5325.
  • Wu, X., Levenston, M. E., & Chaikof, E. L. (2006). A constitutive model for protein-based materials. Biomaterials, 27(30), 5315-5325.
  • Dong, C., Xiaoyi, W. u., Caves, J., Rele, S. S., Thomas, B. S., & Chaikof, E. L. (2005). Photo mediated crosslinking of C6-cinnamate derivatized type I collagen. Biomaterials, 26(18), 4041-4049.
  • Nagapudi, K., Brinkman, W. T., Leisen, J., Thomas, B. S., Wright, E. R., Haller, C., Xiaoyi, W. u., Apkarian, R. P., Conticello, V. P., & Chaikof, E. L. (2005). Protein-based thermoplastic elastomers. Macromolecules, 38(2), 345-354.
  • Sun, X., Haller, C. A., XiaoYi, W. u., Conticello, V. P., & Chaikof, E. L. (2005). One-pot glyco-affinity precipitation purification for enhanced proteomics: The flexible alignment of solution-phase capture/release and solid-phase separation. Journal of Proteome Research, 4(6), 2355-2359.
  • Wu, X., Sallach, R., Haller, C. A., Caves, J. A., Nagapudi, K., Conticello, V. P., Levenston, M. E., & Chaikof, E. L. (2005). Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks. Biomacromolecules, 6(6), 3037-3044.
  • Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The coupled effects of plastic strain gradient and thermal softening on the dynamic growth of voids. International Journal of Solids and Structures, 40(24), 6633-6651.
  • Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The dynamic growth of a single void in a visco plastic material under transient hydrostatic loading. Journal of the Mechanics and Physics of Solids, 51(1), 1-26.
  • Wu, X., Ramesh, K. T., & Wright, T. W. (2003). The effects of thermal softening and heat conduction on the dynamic growth of voids. International Journal of Solids and Structures, 40(17), 4461-4478.

Proceedings Publications

  • Nicolini, A. M., Cohn, C. M., Gamboa, J. R., Slepian, M. J., Wu, X., & Yoon, J. (2014, Apr). Fabrication of a pro-adhesive surface using electro spun PCL nanofibers interspersed with peptide conjugated polystyrene particles. In IEEE-NEMS 2014.

Presentations

  • Cohn, C., Frazer, L., Pearse, M., Leung, S., & Wu, X. (2014, February 28). Engineering Cholesterol-based Nanostructures as Diagnostic Platforms. BME Founder's Day. University of Arizona, Tucson, AZ.
  • Cohn, C., Frazer, L., Pearse, M., Leung, S., & Wu, X. (2014, October 22-25). Engineering Minimally Invasive Diagnostic Platforms with Cholesterol-based Nanostructures. Biomedical Engineering Society Annual Meeting. San Antonio, TX.
  • Nicolini, A. M., Cohn, C. M., Slepian, M. J., Wu, X., & Yoon, J. (2014, Mar). Fabrication of a pro-adhesive surface using electro spun PCL nanofibers interspersed with peptide conjugated polystyrene particles. Annual Meeting of IBE. Lexington, KY: IBE.

Others

  • Wu, X. (2016, May). Bioinspired Materials for Applications in Regenerative Medicine.
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