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Faculty & Staff
Home / Faculty & Staff / Faculty / Kaveh Laksari
Kaveh Laksari
  • klaksari@arizona.edu
    520.621.4307
    Full details at profiles.arizona.edu

Kaveh Laksari

  • Assistant Professor of Biomedical Engineering
  • Assistant Professor of Aerospace and Mechanical Engineering

Degrees

  • Ph.D. Mechanical Engineering
    • Temple University, Philadelphia, Pennsylvania, United States
    • Nonlinear viscoelastic wave propagation in brain tissue.
  • M.S. Mechanical Engineering
    • Temple University, Philadelphia, Pennsylvania, United States
    • Experimental and computational analysis of brain surrogate deformations under linear impact.
  • B.S. Mechanical Engineering
    • University of Tehran, Tehran, Iran, Islamic Republic of

Interests

Teaching

Biomechanics, numerical methods, continuum mechanics, tissue biomechanics

Research

My research focus is on the field of biomechanics in general and injury biomechanics in particular. I have worked on modeling and preventing traumatic brain injury (TBI) in contact sports, and on modeling arteria wall tissue with a focus on high-rate loadings that could lead to loss of mechanical integrity and eventual dissection. I am also working on using high-performance computing to model patient-specific cerebral hemodynamics in stroke patients.

Courses

Independent Study

BME 299 (Spring 2022)
BME 599 (Spring 2019)

Num. Methods in BME

BME 302 (Spring 2019)

Biomechanical Engr

AME 466 (Fall 2022)
AME 466 (Fall 2021)
AME 466 (Fall 2020)
AME 466 (Fall 2018)
AME 466 (Fall 2017)
AME 566 (Fall 2020)
AME 566 (Fall 2019)
AME 566 (Fall 2018)
AME 566 (Fall 2017)
BME 466 (Fall 2022)
BME 466 (Fall 2021)
BME 466 (Fall 2020)
BME 466 (Fall 2019)
BME 466 (Fall 2018)
BME 466 (Fall 2017)
BME 566 (Fall 2022)
BME 566 (Fall 2021)
BME 566 (Fall 2020)
BME 566 (Fall 2019)
BME 566 (Fall 2018)
BME 566 (Fall 2017)

Directed Research

BME 492 (Spring 2021)
BME 492 (Fall 2020)
BME 492 (Fall 2019)
BME 492 (Spring 2019)
BME 492 (Fall 2018)
BME 492 (Spring 2018)

Rsrch Meth Biomed Engr

BME 592 (Fall 2022)
BME 592 (Spring 2022)
BME 592 (Fall 2020)
BME 597G (Fall 2019)
BME 597G (Fall 2018)
BME 597G (Fall 2017)

Special Topics in BME

BME 596 (Spring 2023)

Research

BME 900 (Fall 2020)
BME 900 (Spring 2020)
BME 900 (Fall 2019)

Thesis

AME 910 (Spring 2023)
AME 910 (Fall 2020)
AME 910 (Spring 2020)
BME 910 (Spring 2023)
BME 910 (Spring 2022)
BME 910 (Fall 2021)
BME 910 (Spring 2021)

Dissertation

BME 920 (Spring 2023)
BME 920 (Fall 2022)
BME 920 (Spring 2022)
BME 920 (Fall 2021)
BME 920 (Spring 2021)
BME 920 (Fall 2020)
BME 920 (Spring 2020)
BME 920 (Fall 2019)

Selected Publications

Journals/Publications

  • Laksari, K., Sarabian, M., & Babaee, H. (2022).

    Physics-Informed Neural Networks for Brain Hemodynamic Predictions Using Medical Imaging

    . IEEE Transactions on Medical Imaging, 41(9), 2285-2303. doi:10.1109/tmi.2022.3161653

  • Laksari, K., Toosizadeh, N., Elliott, J., Deshpande, A., Kari, N., Jiang, B., Michel, P., Fahadan, P. T., Kidwell, C., & Wintermark, M. (2022).

    Novel imaging markers for altered cerebrovascular morphology in aging, stroke, and Alzheimer's disease

    . Journal of Neuroimaging, 32(5), 956-967. doi:10.1111/jon.13023

  • Agah, M. R., Laksari, K., & Darvish, K. (2021). Hyperelastic Behavior of Porcine Aorta under Sub-Failure Inflation Loading.
  • Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Mechanical Properties of Brain White Matter under Repetitive Loading Condition: Introducing a Mechanical Damage Function.
  • Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Mind the gap: A mechanobiological hypothesis for the role of gap junctions in the mechanical properties of injured brain tissue. Journal of the mechanical behavior of biomedical materials, 115, 104240.
  • Eskandari, F., Shafieian, M., Aghdam, M. M., & Laksari, K. (2021). Visco-hyperelastic Properties of White and Gray Matters under Tension: an Ex-vivo Study.
  • Laksari, K. (2021). Automatic segmentation, feature extraction and comparison of healthy and stroke cerebral vasculature. NeuroImage: Clinical.
  • Laksari, K. (2021). Mind the gap: A mechanobiological hypothesis for the role of gap junctions in the mechanical properties of injured brain tissue. Journal of the Mechanical Behavior of Biomedical Materials.
  • Laksari, K., & Darvish, K. (2021). Nonlinear Shock Wave Propagation in Soft Tissues as a Mechanism of Injury.
  • Laksari, K., Chou, Y., Grijalva, C., Toosizadeh, N., & Sindorf, J. (2021).

    Dual‐task performance is associated with brain MRI Morphometry in individuals with mild cognitive impairment

    . Journal of Neuroimaging, 31(3), 588-601. doi:10.1111/jon.12845

  • Laksari, K., Witte, R., & Thurgood, H. (2021).

    4D Reconstruction and Identification of Carotid Artery Stenosis Utilizing a Novel Pulsatile Ultrasound Phantom

    . Current Protocols, 1(10). doi:10.1002/cpz1.264

  • Ozkaya, E., Fabris, G., Macruz, F., Suar, Z. M., Abderezaei, J., Su, B., Laksari, K., Wu, L., Camarillo, D. B., Pauly, K. B., & others, . (2021). Viscoelasticity of children and adolescent brains through MR elastography. Journal of the Mechanical Behavior of Biomedical Materials, 115, 104229.
  • Arru'e, P., Toosizadeh, N., Babaee, H., & Laksari, K. (2020). Low-Rank Representation of Head Impact Kinematics: A Data-Driven Emulator. Frontiers in Bioengineering and Biotechnology, 8, 1049.
  • Arrue, P., Toosizadeh, N., Babaee, H., & Laksari, K. (2020). Low-rank representation of head impact kinematics: A data-driven emulator. arXiv preprint arXiv:2004.12979.
  • Deshpande, A., Jamilpour, N., Jiang, B., Kidwell, C., Wintermark, M., & Laksari, K. (2020). Automatic Segmentation, Feature Extraction and Comparison of Healthy and Stroke Cerebral Vasculature. arXiv preprint arXiv:2002.11208.

Proceedings Publications

  • Kamali, A., Dieckhaus, L. A., Peters, E., Hutchinson, E. B., Laksari, K., & Pires, P. (2021, Oct.). The Golden Hour: Early outcomes of traumatic brain injury and stroke. In Biomedical Engineering Society.
  • Agah, M. R., Laksari, K., & Darvish, K. (2012, June). Hyperelastic Behavior of Porcine Aorta under Sub-Failure Inflation Loading. In Summer Bioengineering Conference.
  • Laksari, K., Darvish, K., & Sadeghipour, K. (2012, May). Nonlinear Shock Wave Propagation in Soft Tissues as a Mechanism of Injury. In Injury Biomechanics Symposium.
  • Laksari, K., Wu, L., Nguyen, T., Kurt, M., Fanton, M., Ruan, J., Barbat, S., & Camarillo, D. (2017). MULTI-DIRECTIONAL DYNAMIC INJURY METRIC FOR MILD BRAIN TRAUMA DETECTION. In JOURNAL OF NEUROTRAUMA, 34.
  • Assari, S., Laksari, K., Barbe, M., & Darvish, K. (2013). Cerebral blood pressure rise during blast exposure in a rat model of blast-induced traumatic brain injury. In ASME 2013 International Mechanical Engineering Congress and Exposition.
  • Assari, S., Laksari, K., Barbe, M., & Darvish, K. (2013). Cerebral blood pressure rise during blast exposure in a rat model of blast-induced traumatic brain injury. In From the ASME 2013 International Mechanical Engineering Congress and Exposition, 3.
  • Kermani, G., Laksari, K., & Darvish, K. (2013). Biomechanical Properties of Human Aorta from Dynamic Biaxial Loading. In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast.
  • Laksari, K., Assari, S., & Darvish, K. (2013). COMPUTATIONAL COMPARISON OF SHOCK WAVE PROPOAGATION IN EXPLOSIVE BLAST AND SHOCK TUBE EXPERIMENTS. In ASME 2013 International Mechanical Engineering Congress and Exposition.
  • Laksari, K., Assari, S., & Darvish, K. (2013). Computational Comparison of Shock Wave Propagation in Explosive Blast and Shock Tube Experiments. In ASME International Mechanical Engineering Congress and Exposition, 56215.
  • Laksari, K., Assari, S., & Darvish, K. (2013). Computational Simulation of Shock Tube and the Effect of Shock Thickness on Strain-Rates. In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast.
  • Agah, M. R., Laksari, K., & Darvish, K. (2012). Investigating the hyperelasticity of porcine aorta under sub-failure loading. In Bioengineering Conference (NEBEC), 2012 38th Annual Northeast.
  • Agah, M. R., Laksari, K., Darvish, K., & Rachev, A. (2012). Buckling of Porcine Aorta under Static and Dynamic Loading. In American Society of Mechanical Engineering Summer Bioengineering Conference.
  • Laksari, K., Agah, M. R., & Darvish, K. (2012). Hyperelastic Behavior of Porcine Aorta in Sub-Injury Pressures. In American Society of Mechanical Engineering Summer Bioengineering Conference.
  • Laksari, K., Agah, M. R., Rachev, A., & Darvish, K. (2012). Investigating the effects of dynamic and static loading on the stability of porcine aorta. In Bioengineering Conference (NEBEC), 2012 38th Annual Northeast.
  • Shafieian, M., Laksari, K., Darvish, K., & Crandall, J. (2012). Development of a constitutive model for brain tissue under multiaxial loading. In Proceedings of the 2012 International IRCOBI Conference on the Biomechanics of Injury.

Others

  • Kuo, C., Wu, L. C., Laksari, K., & Camarillo, D. B. (2017). Oral appliance for measuring head motions by isolating sensors from jaw perturbance.
  • Hernandez, F., Laksari, K., & Camarillo, D. B. (2015). System for redirecting head impact force.
  • Laksari, K. (2013). Nonlinear viscoelastic wave propagation in brain tissue.
  • Laksari, K. (2009). Experimental and Computational Analysis of Brain Surrogate Material Under Linear Impact.

Awards

  • Flinn Foundation limited submission
    • I was selected as the institutional submission for the Flinn Foundation program limited submission (8/18/21), Summer I 2021
  • 2021 Vevo Research Award
    • Our work on investigating the effects of traumatic brain injury in mice using photoacoustic and ultrasound imaging won the 2021 Vevo Research Award sponsored by Fuji Film (Collaboration with Beth Hutchinson, Russ Witte, Paulo Pires), Summer I 2021
  • Pew Biomedical Schilar limited submission
    • I was selected as the institutional submission for the Pew Biomedical Scholars program limited submission, Spring 2021
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The University of Arizona
Department of Aerospace & Mechanical Engineering
1130 N. Mountain Ave.
P.O. Box 210119
Tucson, AZ 85721
520.626.2053

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